Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL3413255

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of Trypanosoma cruzi cruzaine in absence of 0.01% Triton
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Trypanosoma cruzi
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Cruzipain (CHEMBL3563)
Type SINGLE PROTEIN
Organism Trypanosoma cruzi

Publication

Computer-guided drug repurposing: identification of trypanocidal activity of clofazimine, benidipine and saquinavir.
Bellera CL, Balcazar DE, Vanrell MC, Casassa AF, Palestro PH, Gavernet L, Labriola CA, Gálvez J, Bruno-Blanch LE, Romano PS, Carrillo C, Talevi A.
Eur J Med Chem (2015) 93 : 338 -348
PubMed 25707014 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.22 5.22

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1292 CLOFAZIMINE 4.0 1 5.22

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1292 CLOFAZIMINE IC50 = 6000.0 nM 5.22