Assay Detail
Binding
CHEMBL3418128
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of baker's yeast alpha-glucosidase using p-nitrophenyl-alpha-D-glucopyranoside substrate assessed as inhibition constant for enzyme-compound binding by measuring reduction in p-nitrophenolate formation
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Saccharomyces bayanus |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Phenolic thio- and selenosemicarbazones as multi-target drugs.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 9 | 4.57 | 5.02 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2296747 | — | — | 1 | 5.02 |
| CHEMBL3415890 | — | — | 1 | 4.52 |
| CHEMBL3415893 | — | — | 1 | 4.48 |
| CHEMBL3415892 | — | — | 1 | 4.24 |
| CHEMBL3415886 | — | — | 1 | - |
| CHEMBL3415887 | — | — | 1 | - |
| CHEMBL3415888 | — | — | 1 | - |
| CHEMBL3415889 | — | — | 1 | - |
| CHEMBL3415894 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2296747 | — | Ki | = | 9600.0 | nM | 5.02 |
| CHEMBL3415890 | — | Ki | = | 30300.0 | nM | 4.52 |
| CHEMBL3415893 | — | Ki | = | 33000.0 | nM | 4.48 |
| CHEMBL3415892 | — | Ki | = | 57800.0 | nM | 4.24 |
| CHEMBL3415886 | — | Ki | = | 707600.0 | nM | - |
| CHEMBL3415887 | — | Ki | = | 297000.0 | nM | - |
| CHEMBL3415888 | — | Ki | = | 335800.0 | nM | - |
| CHEMBL3415889 | — | Ki | = | 201200.0 | nM | - |
| CHEMBL3415894 | — | Ki | = | 153600.0 | nM | - |