Assay Detail
Binding
CHEMBL3418129
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of baker's yeast alpha-glucosidase using p-nitrophenyl-alpha-D-glucopyranoside substrate assessed as inhibition constant for enzyme-substrate-compound binding by measuring reduction in p-nitrophenolate formation
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Saccharomyces bayanus |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Phenolic thio- and selenosemicarbazones as multi-target drugs.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 8 | 4.14 | 4.23 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3415891 | — | — | 1 | 4.23 |
| CHEMBL3415892 | — | — | 1 | 4.16 |
| CHEMBL3415894 | — | — | 1 | 4.15 |
| CHEMBL3415893 | — | — | 1 | 4.12 |
| CHEMBL3415890 | — | — | 1 | 4.11 |
| CHEMBL3415887 | — | — | 1 | 4.06 |
| CHEMBL456610 | — | — | 1 | - |
| CHEMBL3415886 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3415891 | — | Ki | = | 59000.0 | nM | 4.23 |
| CHEMBL3415892 | — | Ki | = | 69800.0 | nM | 4.16 |
| CHEMBL3415894 | — | Ki | = | 70300.0 | nM | 4.15 |
| CHEMBL3415893 | — | Ki | = | 76800.0 | nM | 4.12 |
| CHEMBL3415890 | — | Ki | = | 78400.0 | nM | 4.11 |
| CHEMBL3415887 | — | Ki | = | 86200.0 | nM | 4.06 |
| CHEMBL456610 | — | Ki | = | 213000.0 | nM | - |
| CHEMBL3415886 | — | Ki | = | 134400.0 | nM | - |