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Assay Detail

CHEMBL3419861

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity PSMA (unknown origin)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Glutamate carboxypeptidase 2 (CHEMBL1892)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

DUPA conjugation of a cytotoxic indenoisoquinoline topoisomerase I inhibitor for selective prostate cancer cell targeting.
Roy J, Nguyen TX, Kanduluru AK, Venkatesh C, Lv W, Reddy PV, Low PS, Cushman M.
J Med Chem (2015) 58 : 3094 -3103
PubMed 25822623 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 8.10 8.10

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL46005 1 8.10

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL46005 Ki = 8.0 nM 8.10