Assay Detail
Functional
CHEMBL3420293
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of cell proliferation of human NCI-H661 cells after 72 hrs by SRB assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | NCI-H661 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Enhancing the cellular anti-proliferation activity of pyridazinones as c-met inhibitors using docking analysis.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.80 | 5.80 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3417482 | — | — | 1 | 5.80 |
| CHEMBL3417489 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3417482 | — | IC50 | = | 1600.0 | nM | 5.80 |
| CHEMBL3417489 | — | IC50 | > | 10000000.0 | nM | - |