Assay Detail
Binding
CHEMBL3424167
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of recombinant activated DDR2 tyrosine kinase domain (unknown origin) using histone H2B peptide substrate and [32P]ATP incubated for 15 mins
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Discoidin domain-containing receptor 2 (CHEMBL5122) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Small molecule discoidin domain receptor kinase inhibitors and potential medical applications.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 8.22 | 8.22 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2336005 | — | — | 1 | 8.22 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2336005 | — | IC50 | = | 6.0 | nM | 8.22 |