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Assay Detail

CHEMBL3424561

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against human MDA-MB-231 cells after 72 hrs by MTT assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type MDA-MB-231
Confidence 1 — Organism
Curated By Autocuration

Target

MDA-MB-231 (CHEMBL400)
Type CELL-LINE
Organism Homo sapiens

Publication

Discovery of autophagy inhibitors with antiproliferative activity in lung and pancreatic cancer cells.
Nordstrøm LU, Sironi J, Aranda E, Maisonet J, Perez-Soler R, Wu P, Schwartz EL.
ACS Med Chem Lett (2015) 6 : 134 -139
PubMed 25699157 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.24 5.24

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL279014 LUCANTHONE 2.0 1 5.24

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL279014 LUCANTHONE IC50 = 5700.0 nM 5.24