Assay Detail
Binding
CHEMBL3427962
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of CXCR2 (unknown origin) transfected with RBL cells
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | RBL |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Boronic acid-containing CXCR1/2 antagonists: Optimization of metabolic stability, in vivo evaluation, and a proposed receptor binding model.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.07 | 7.68 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3426944 | — | — | 1 | 7.68 |
| CHEMBL3342269 | — | — | 1 | 6.45 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3426944 | — | IC50 | = | 21.0 | nM | 7.68 |
| CHEMBL3342269 | — | IC50 | = | 356.0 | nM | 6.45 |