Assay Detail

CHEMBL3428131

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Functional

Antimalarial activity against Plasmodium falciparum D7

ChEMBL ↗

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Target

Plasmodium falciparum (CHEMBL364) ↗

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Primary target Plasmodium falciparum

CHEMBL364

Anchored from Assay target.

Protein identity Plasmodium falciparum

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Plasmodium falciparum
Confidence	1 — Organism
Curated By	Autocuration

Target

Plasmodium falciparum (CHEMBL364) ↗

Type	ORGANISM
Organism	Plasmodium falciparum

Publication

Synthesis, antimalarial and antitubercular activities of meridianin derivatives.

Yadav RR, Khan SI, Singh S, Khan IA, Vishwakarma RA, Bharate SB.
Eur J Med Chem (2015) 98 : 160 -169
PubMed 26005918 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	1	4.92	4.92

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL50498	MERIDIANIN A	—	1	4.92

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL50498	MERIDIANIN A	IC50	=	12000.0	nM	4.92