Assay Detail
Binding
CHEMBL3429698
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of PI4K3beta (unknown origin) assessed as hydrolysis of ATP for 60 mins by ADP-Glo kinase assay
11
Total Activities
11
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Highly Selective Phosphatidylinositol 4-Kinase IIIβ Inhibitors and Structural Insight into Their Mode of Action.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 11 | 7.05 | 7.27 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3426601 | — | — | 1 | 7.27 |
| CHEMBL3426597 | — | — | 1 | 7.17 |
| CHEMBL3426594 | — | — | 1 | 7.16 |
| CHEMBL3426603 | — | — | 1 | 7.08 |
| CHEMBL3426600 | — | — | 1 | 7.05 |
| CHEMBL3426599 | — | — | 1 | 7.05 |
| CHEMBL3426602 | — | — | 1 | 7.04 |
| CHEMBL3426598 | — | — | 1 | 7.03 |
| CHEMBL3426596 | — | — | 1 | 6.92 |
| CHEMBL3426595 | — | — | 1 | 6.92 |
| CHEMBL2397317 | — | — | 1 | 6.82 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3426601 | — | IC50 | = | 54.0 | nM | 7.27 |
| CHEMBL3426597 | — | IC50 | = | 67.0 | nM | 7.17 |
| CHEMBL3426594 | — | IC50 | = | 70.0 | nM | 7.16 |
| CHEMBL3426603 | — | IC50 | = | 83.0 | nM | 7.08 |
| CHEMBL3426600 | — | IC50 | = | 89.0 | nM | 7.05 |
| CHEMBL3426599 | — | IC50 | = | 90.0 | nM | 7.05 |
| CHEMBL3426602 | — | IC50 | = | 92.0 | nM | 7.04 |
| CHEMBL3426598 | — | IC50 | = | 93.0 | nM | 7.03 |
| CHEMBL3426596 | — | IC50 | = | 120.0 | nM | 6.92 |
| CHEMBL3426595 | — | IC50 | = | 120.0 | nM | 6.92 |
| CHEMBL2397317 | — | IC50 | = | 150.0 | nM | 6.82 |