Assay Detail
Binding
CHEMBL3429699
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Inhibition of PI4K3alpha (unknown origin) assessed as hydrolysis of ATP for 60 mins by ADP-Glo kinase assay
11
Total Activities
11
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Highly Selective Phosphatidylinositol 4-Kinase IIIβ Inhibitors and Structural Insight into Their Mode of Action.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 11 | 4.34 | 4.56 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3426598 | — | — | 1 | 4.56 |
| CHEMBL3426597 | — | — | 1 | 4.53 |
| CHEMBL3426596 | — | — | 1 | 4.53 |
| CHEMBL3426602 | — | — | 1 | 4.47 |
| CHEMBL3426594 | — | — | 1 | 4.23 |
| CHEMBL3426595 | — | — | 1 | 4.21 |
| CHEMBL2397317 | — | — | 1 | 4.13 |
| CHEMBL3426599 | — | — | 1 | 4.08 |
| CHEMBL3426603 | — | — | 1 | - |
| CHEMBL3426601 | — | — | 1 | - |
| CHEMBL3426600 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3426598 | — | IC50 | = | 27460.0 | nM | 4.56 |
| CHEMBL3426597 | — | IC50 | = | 29520.0 | nM | 4.53 |
| CHEMBL3426596 | — | IC50 | = | 29310.0 | nM | 4.53 |
| CHEMBL3426602 | — | IC50 | = | 33670.0 | nM | 4.47 |
| CHEMBL3426594 | — | IC50 | = | 59450.0 | nM | 4.23 |
| CHEMBL3426595 | — | IC50 | = | 62140.0 | nM | 4.21 |
| CHEMBL2397317 | — | IC50 | = | 74550.0 | nM | 4.13 |
| CHEMBL3426599 | — | IC50 | = | 82670.0 | nM | 4.08 |
| CHEMBL3426603 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL3426601 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL3426600 | — | IC50 | > | 100000.0 | nM | - |