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Assay Detail

CHEMBL3430294

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to human CLK2
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Dual specificity protein kinase CLK2 (CHEMBL4225)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Selective Inhibitors of Cyclin G Associated Kinase (GAK) as Anti-Hepatitis C Agents.
Kovackova S, Chang L, Bekerman E, Neveu G, Barouch-Bentov R, Chaikuad A, Heroven C, Šála M, De Jonghe S, Knapp S, Einav S, Herdewijn P.
J Med Chem (2015) 58 : 3393 -3410
PubMed 25822739 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 1 6.15 6.15

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3425865 1 6.15

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3425865 Kd = 710.0 nM 6.15