Assay Detail
Functional
CHEMBL3430600
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of voltage-gated L-type Ca channel (species unknown)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Confidence | 4 — Cell-line / Tissue |
| Curated By | Autocuration |
Target
Voltage-gated L-type calcium channel (CHEMBL2095229) ↗| Type | PROTEIN FAMILY |
| Organism | Homo sapiens |
Publication
Simulation of multiple ion channel block provides improved early prediction of compounds' clinical torsadogenic risk.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 6.57 | 6.57 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL633 | AMIODARONE | 4.0 | 1 | 6.57 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL633 | AMIODARONE | IC50 | = | 270.0 | nM | 6.57 |