Assay Detail
Binding
CHEMBL3532880
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of glycogen phosphorylase in rat hepatocytes assessed as reduction in basal glycogenolysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Cell Type | Hepatocyte |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Glycogen phosphorylase, liver form (CHEMBL3239) ↗| Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
Publication
Absorption, elimination, and metabolism of CS-1036, a novel α-amylase inhibitor in rats and monkeys, and the relationship between gastrointestinal distribution and suppression of glucose absorption.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 6.00 | 6.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL80254 | — | — | 1 | 6.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL80254 | — | IC50 | = | 1000.0 | nM | 6.00 |