Assay Detail
Binding
CHEMBL3578767
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of ROCK2 (unknown origin) using substrate FITC-AHA- AKRRRLSSLRA-OH
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Rho kinase inhibitors: potentially versatile therapy for the treatment of cardiovascular diseases and more.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 8.24 | 9.74 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3578252 | — | — | 1 | 9.74 |
| CHEMBL3578250 | — | — | 1 | 9.29 |
| CHEMBL3578253 | — | — | 1 | 8.94 |
| CHEMBL3578251 | — | — | 1 | 5.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3578252 | — | IC50 | = | 0.18 | nM | 9.74 |
| CHEMBL3578250 | — | IC50 | = | 0.51 | nM | 9.29 |
| CHEMBL3578253 | — | IC50 | = | 1.16 | nM | 8.94 |
| CHEMBL3578251 | — | IC50 | = | 9920.0 | nM | 5.00 |