Assay Detail
Functional
CHEMBL3579502
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Antibacterial activity against Bacillus subtilis ATCC 6633 after 24 hrs by spectrophotometric analysis
8
Total Activities
4
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Bacillus spizizenii |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Aranciamycins I and J, Antimycobacterial Anthracyclines from an Australian Marine-Derived Streptomyces sp.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.48 | 5.62 |
| MIC | 4 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3577668 | — | — | 2 | 5.62 |
| CHEMBL3577667 | — | — | 2 | 5.55 |
| CHEMBL3577666 | — | — | 2 | 5.52 |
| CHEMBL1096602 | ARANCIAMYCIN | — | 2 | 5.24 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3577668 | — | IC50 | = | 2400.0 | nM | 5.62 |
| CHEMBL3577667 | — | IC50 | = | 2800.0 | nM | 5.55 |
| CHEMBL3577666 | — | IC50 | = | 3000.0 | nM | 5.52 |
| CHEMBL1096602 | ARANCIAMYCIN | IC50 | = | 5800.0 | nM | 5.24 |
| CHEMBL3577666 | — | MIC | = | 7500.0 | nM | - |
| CHEMBL3577667 | — | MIC | = | 7500.0 | nM | - |
| CHEMBL3577668 | — | MIC | = | 7500.0 | nM | - |
| CHEMBL1096602 | ARANCIAMYCIN | MIC | = | 15000.0 | nM | - |