Assay Detail
Functional
CHEMBL3579509
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Cytotoxicity against human HepG2 cells assessed as growth inhibition after 48 hrs by MTT assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HepG2 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Aranciamycins I and J, Antimycobacterial Anthracyclines from an Australian Marine-Derived Streptomyces sp.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 4.86 | 4.92 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3577666 | — | — | 1 | 4.92 |
| CHEMBL3577667 | — | — | 1 | 4.92 |
| CHEMBL1096602 | ARANCIAMYCIN | — | 1 | 4.75 |
| CHEMBL3577668 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3577666 | — | IC50 | = | 12000.0 | nM | 4.92 |
| CHEMBL3577667 | — | IC50 | = | 12000.0 | nM | 4.92 |
| CHEMBL1096602 | ARANCIAMYCIN | IC50 | = | 18000.0 | nM | 4.75 |
| CHEMBL3577668 | — | IC50 | > | 30000.0 | nM | - |