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Assay Detail

CHEMBL3579561

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Functional
Antiplasmodium activity against Plasmodium falciparum Dd2
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Plasmodium falciparum
Confidence 1 — Organism
Curated By Autocuration

Target

Plasmodium falciparum (CHEMBL364)
Type ORGANISM
Organism Plasmodium falciparum

Publication

Neolignans and other metabolites from Ocotea cymosa from the Madagascar rain forest and their biological activities.
Rakotondraibe LH, Graupner PR, Xiong Q, Olson M, Wiley JD, Krai P, Brodie PJ, Callmander MW, Rakotobe E, Ratovoson F, Rasamison VE, Cassera MB, Hahn DR, Kingston DG, Fotso S.
J Nat Prod (2015) 78 : 431 -440
PubMed 25650896 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 5 4.83 5.51

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3577103 1 5.51
CHEMBL3577183 1 5.33
CHEMBL3577189 1 4.55
CHEMBL3577191 1 4.39
CHEMBL3577101 1 4.38

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3577103 IC50 = 3100.0 nM 5.51
CHEMBL3577183 IC50 = 4700.0 nM 5.33
CHEMBL3577189 IC50 = 28400.0 nM 4.55
CHEMBL3577191 IC50 = 40500.0 nM 4.39
CHEMBL3577101 IC50 = 42100.0 nM 4.38