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Assay Detail

CHEMBL3579820

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Physicochemical
Antioxidant activity assessed as DPPH radical scavenging activity after 1 hr
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Physicochemical
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Publication

Selenium-containing chrysin and quercetin derivatives: attractive scaffolds for cancer therapy.
Martins IL, Charneira C, Gandin V, Ferreira da Silva JL, Justino GC, Telo JP, Vieira AJ, Marzano C, Antunes AM.
J Med Chem (2015) 58 : 4250 -4265
PubMed 25906385 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 5 4.63 5.22

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL196 ASCORBIC ACID 4.0 1 5.22
CHEMBL50 QUERCETIN 3.0 1 4.55
CHEMBL3578022 1 4.13
CHEMBL3578021 1 -
CHEMBL3578023 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL196 ASCORBIC ACID IC50 = 6000.0 nM 5.22
CHEMBL50 QUERCETIN IC50 = 28000.0 nM 4.55
CHEMBL3578022 IC50 = 74000.0 nM 4.13
CHEMBL3578021 IC50 = 4600000.0 nM -
CHEMBL3578023 IC50 = 659000.0 nM -