Assay Detail
Functional
CHEMBL3580017
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Antiproliferative activity against human K562 cells assessed as vitality after 72 hrs by automatic cell counting analysis
11
Total Activities
11
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | K562 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Studies on the ATP Binding Site of Fyn Kinase for the Identification of New Inhibitors and Their Evaluation as Potential Agents against Tauopathies and Tumors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 11 | 5.89 | 6.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3578215 | — | — | 1 | 6.52 |
| CHEMBL3578214 | — | — | 1 | 6.25 |
| CHEMBL3578213 | — | — | 1 | 4.90 |
| CHEMBL3578223 | — | — | 1 | - |
| CHEMBL3578222 | — | — | 1 | - |
| CHEMBL3578221 | — | — | 1 | - |
| CHEMBL3578220 | — | — | 1 | - |
| CHEMBL3578219 | — | — | 1 | - |
| CHEMBL3578218 | — | — | 1 | - |
| CHEMBL3578217 | — | — | 1 | - |
| CHEMBL3578216 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3578215 | — | IC50 | = | 300.0 | nM | 6.52 |
| CHEMBL3578214 | — | IC50 | = | 560.0 | nM | 6.25 |
| CHEMBL3578213 | — | IC50 | = | 12630.0 | nM | 4.90 |
| CHEMBL3578223 | — | IC50 | - | — | - | |
| CHEMBL3578222 | — | IC50 | - | — | - | |
| CHEMBL3578221 | — | IC50 | - | — | - | |
| CHEMBL3578220 | — | IC50 | - | — | - | |
| CHEMBL3578219 | — | IC50 | - | — | - | |
| CHEMBL3578218 | — | IC50 | - | — | - | |
| CHEMBL3578217 | — | IC50 | - | — | - | |
| CHEMBL3578216 | — | IC50 | - | — | - |