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Assay Detail

CHEMBL3582892

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiviral activity against picornavirus infected in CB1 cells assessed as inhibition of viral replication after 3 days by MTT assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Picornaviridae
Cell Type CB1
Confidence 1 — Organism
Curated By Autocuration

Target

Picornaviridae (CHEMBL613008)
Type ORGANISM
Organism Picornaviridae

Publication

Structure-Activity Relationships of Neplanocin A Analogues as S-Adenosylhomocysteine Hydrolase Inhibitors and Their Antiviral and Antitumor Activities.
Chandra G, Moon YW, Lee Y, Jang JY, Song J, Nayak A, Oh K, Mulamoottil VA, Sahu PK, Kim G, Chang TS, Noh M, Lee SK, Choi S, Jeong LS.
J Med Chem (2015) 58 : 5108 -5120
PubMed 26010585 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 5.63 5.63

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3580896 1 5.63

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3580896 EC50 = 2340.0 nM 5.63