Assay Detail
Binding
CHEMBL3587209
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Activity at human PPARgamma transfected in HEK293 cells assessed as transactivation activity by luciferase reporter gene assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | HEK293 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Peroxisome proliferator-activated receptor gamma (CHEMBL235) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Peroxisome Proliferator-Activated Receptor γ (PPARγ) and Ligand Choreography: Newcomers Take the Stage.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 5 | 6.24 | 7.24 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL370152 | — | — | 1 | 7.24 |
| CHEMBL3585572 | — | — | 1 | 6.81 |
| CHEMBL491820 | AMORFRUTIN A | — | 1 | 6.34 |
| CHEMBL1204498 | — | — | 1 | 5.89 |
| CHEMBL2103824 | ARHALOFENATE | 2.0 | 1 | 4.92 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL370152 | — | EC50 | = | 57.0 | nM | 7.24 |
| CHEMBL3585572 | — | EC50 | = | 155.0 | nM | 6.81 |
| CHEMBL491820 | AMORFRUTIN A | EC50 | = | 458.0 | nM | 6.34 |
| CHEMBL1204498 | — | EC50 | = | 1300.0 | nM | 5.89 |
| CHEMBL2103824 | ARHALOFENATE | EC50 | = | 12000.0 | nM | 4.92 |