Assay Detail
Binding
CHEMBL3587211
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Activity at PPARgamma (unknown origin) assessed as transactivation activity by reporter gene assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Peroxisome proliferator-activated receptor gamma (CHEMBL235) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Peroxisome Proliferator-Activated Receptor γ (PPARγ) and Ligand Choreography: Newcomers Take the Stage.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 4 | 7.77 | 9.42 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3585575 | — | — | 1 | 9.42 |
| CHEMBL1729254 | — | — | 1 | 7.14 |
| CHEMBL3585576 | — | — | 1 | 6.74 |
| CHEMBL3348830 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3585575 | — | EC50 | = | 0.38 | nM | 9.42 |
| CHEMBL1729254 | — | EC50 | = | 73.0 | nM | 7.14 |
| CHEMBL3585576 | — | EC50 | = | 183.0 | nM | 6.74 |
| CHEMBL3348830 | — | EC50 | - | — | - |