Assay Detail
Functional
CHEMBL3588049
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Reduction in TNFalpha-induced PPARgamma expression in human HT-29 cells after 48 hrs by Western blotting analysis
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HT-29 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Amorfrutins Are Natural PPARγ Agonists with Potent Anti-inflammatory Properties.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.41 | 4.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2337127 | — | — | 1 | 4.52 |
| CHEMBL491820 | AMORFRUTIN A | — | 1 | 4.29 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2337127 | — | IC50 | = | 30500.0 | nM | 4.52 |
| CHEMBL491820 | AMORFRUTIN A | IC50 | = | 50800.0 | nM | 4.29 |