Assay Detail
Binding
CHEMBL3588104
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Binding affinity to 5' FAM/3' TAMRA labeled HRAS1 G-quadruplex DNA (unknown origin) by FRET analysis
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Not specified |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Potent Apoptotic Response Induced by Chloroacetamidine Anthrathiophenediones in Bladder Cancer Cells.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 5 | 6.59 | 6.75 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3586306 | — | — | 1 | 6.75 |
| CHEMBL3586305 | — | — | 1 | 6.75 |
| CHEMBL3586308 | — | — | 1 | 6.64 |
| CHEMBL3586307 | — | — | 1 | 6.58 |
| CHEMBL3586304 | — | — | 1 | 6.21 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3586306 | — | Kd | = | 178.0 | nM | 6.75 |
| CHEMBL3586305 | — | Kd | = | 179.0 | nM | 6.75 |
| CHEMBL3586308 | — | Kd | = | 231.0 | nM | 6.64 |
| CHEMBL3586307 | — | Kd | = | 260.0 | nM | 6.58 |
| CHEMBL3586304 | — | Kd | = | 611.0 | nM | 6.21 |