Assay Detail
Binding
CHEMBL3591973
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Competitive Inhibition of Electrophorus electricus acetylcholinesterase using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition measured for 30 mins by Ellman's method
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Electrophorus electricus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Allobetulin derived seco-oleananedicarboxylates act as inhibitors of acetylcholinesterase.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 5.31 | 5.48 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3586232 | — | — | 1 | 5.48 |
| CHEMBL3590226 | — | — | 1 | 5.47 |
| CHEMBL3586240 | — | — | 1 | 4.98 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3586232 | — | Ki | = | 3330.0 | nM | 5.48 |
| CHEMBL3590226 | — | Ki | = | 3390.0 | nM | 5.47 |
| CHEMBL3586240 | — | Ki | = | 10450.0 | nM | 4.98 |