Assay Detail
Binding
CHEMBL3591975
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Uncompetitive Inhibition of Electrophorus electricus acetylcholinesterase using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition measured for 30 mins by Ellman's method
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Electrophorus electricus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Allobetulin derived seco-oleananedicarboxylates act as inhibitors of acetylcholinesterase.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 5.47 | 5.61 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3586232 | — | — | 1 | 5.61 |
| CHEMBL3586240 | — | — | 1 | 5.33 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3586232 | — | Ki | = | 2480.0 | nM | 5.61 |
| CHEMBL3586240 | — | Ki | = | 4630.0 | nM | 5.33 |