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Assay Detail

CHEMBL3592000

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to Pseudomonas aeruginosa LecA
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Pseudomonas aeruginosa
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Towards bacterial adhesion-based therapeutics and detection methods
Pera NP, Pieters RJ
Medchemcomm (2014) 5 : 1027 -1035
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 9 5.76 7.55

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3590186 1 7.55
CHEMBL3590175 1 7.10
CHEMBL3590174 1 7.05
CHEMBL3589832 1 5.38
CHEMBL3589830 1 5.38
CHEMBL3589831 1 5.24
CHEMBL3590184 1 5.20
CHEMBL157265 1 4.85
CHEMBL6067641 GALACTOSE 3.0 1 4.06

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3590186 Kd = 28.0 nM 7.55
CHEMBL3590175 Kd = 79.0 nM 7.10
CHEMBL3590174 Kd = 90.0 nM 7.05
CHEMBL3589832 Kd = 4200.0 nM 5.38
CHEMBL3589830 Kd = 4200.0 nM 5.38
CHEMBL3589831 Kd = 5800.0 nM 5.24
CHEMBL3590184 Kd = 6300.0 nM 5.20
CHEMBL157265 Kd = 14100.0 nM 4.85
CHEMBL6067641 GALACTOSE Kd = 87500.0 nM 4.06