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Assay Detail

CHEMBL3592001

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to Pseudomonas aeruginosa LecB
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Pseudomonas aeruginosa
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Towards bacterial adhesion-based therapeutics and detection methods
Pera NP, Pieters RJ
Medchemcomm (2014) 5 : 1027 -1035
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 6 5.52 6.68

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3590185 1 6.68
CHEMBL3590171 1 6.54
CHEMBL6067643 L-FUCOSE 3.0 1 5.52
CHEMBL3590172 1 5.48
CHEMBL3590173 1 4.73
CHEMBL3590182 1 4.15

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3590185 Kd = 210.0 nM 6.68
CHEMBL3590171 Kd = 290.0 nM 6.54
CHEMBL6067643 L-FUCOSE Kd = 3000.0 nM 5.52
CHEMBL3590172 Kd = 3300.0 nM 5.48
CHEMBL3590173 Kd = 18500.0 nM 4.73
CHEMBL3590182 Kd = 71000.0 nM 4.15