Assay Detail
Binding
CHEMBL3592955
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Inhibition of HIV integrase strand transfer activity
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Human immunodeficiency virus |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
The biology and synthesis of α-hydroxytropolones.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.69 | 6.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL335048 | — | — | 1 | 6.10 |
| CHEMBL3588901 | — | — | 1 | 5.92 |
| CHEMBL3589937 | — | — | 1 | 5.77 |
| CHEMBL135189 | — | — | 1 | 4.96 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL335048 | — | IC50 | = | 800.0 | nM | 6.10 |
| CHEMBL3588901 | — | IC50 | = | 1200.0 | nM | 5.92 |
| CHEMBL3589937 | — | IC50 | = | 1700.0 | nM | 5.77 |
| CHEMBL135189 | — | IC50 | = | 11000.0 | nM | 4.96 |