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Assay Detail

CHEMBL3592957

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of hepatitis B virus genotype D RNaseH
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Hepatitis B virus
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

The biology and synthesis of α-hydroxytropolones.
Meck C, D'Erasmo MP, Hirsch DR, Murelli RP.
Medchemcomm (2014) 5 : 842 -852
PubMed 25089179 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 5.42 5.60

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1270611 1 5.60
CHEMBL550937 BETA-THUJAPLICINOL 1 5.23

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1270611 IC50 = 2500.0 nM 5.60
CHEMBL550937 BETA-THUJAPLICINOL IC50 = 5900.0 nM 5.23