Assay Detail
Functional
CHEMBL3593053
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Antimalarial activity against Plasmodium falciparum FCR-3/Gambia
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Plasmodium falciparum |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
The biology and synthesis of α-hydroxytropolones.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.99 | 8.60 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL361497 | ARTESUNATE | 4.0 | 1 | 8.60 |
| CHEMBL3588897 | — | — | 1 | 7.30 |
| CHEMBL3357560 | — | — | 1 | 5.06 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL361497 | ARTESUNATE | IC50 | = | 2.5 | nM | 8.60 |
| CHEMBL3588897 | — | IC50 | = | 50.0 | nM | 7.30 |
| CHEMBL3357560 | — | IC50 | = | 8700.0 | nM | 5.06 |