Assay Detail
Binding
CHEMBL3593062
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Inhibition of HIV2 reverse transcriptase RNase H
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Human immunodeficiency virus 2 |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
The biology and synthesis of α-hydroxytropolones.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.29 | 6.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL550937 | BETA-THUJAPLICINOL | — | 1 | 6.10 |
| CHEMBL1275969 | ALPHA-THUJAPLICIN | — | 1 | 4.48 |
| CHEMBL121188 | TROPOLONE | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL550937 | BETA-THUJAPLICINOL | IC50 | = | 800.0 | nM | 6.10 |
| CHEMBL1275969 | ALPHA-THUJAPLICIN | IC50 | = | 33000.0 | nM | 4.48 |
| CHEMBL121188 | TROPOLONE | IC50 | > | 100000.0 | nM | - |