Assay Detail
Binding
CHEMBL3593064
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human ribonuclease H
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Escherichia coli |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
The biology and synthesis of α-hydroxytropolones.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.23 | 5.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL121188 | TROPOLONE | — | 1 | 5.52 |
| CHEMBL550937 | BETA-THUJAPLICINOL | — | 1 | 5.24 |
| CHEMBL1275969 | ALPHA-THUJAPLICIN | — | 1 | 4.92 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL121188 | TROPOLONE | IC50 | = | 3000.0 | nM | 5.52 |
| CHEMBL550937 | BETA-THUJAPLICINOL | IC50 | = | 5700.0 | nM | 5.24 |
| CHEMBL1275969 | ALPHA-THUJAPLICIN | IC50 | = | 12000.0 | nM | 4.92 |