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Assay Detail

CHEMBL3594583

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Physicochemical
Antioxidant activity assessed as DPPH radical scavenging activity after 30 min
18
Total Activities
18
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Physicochemical
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Publication

Synthesis of (2-amino)ethyl derivatives of quercetin 3-O-methyl ether and their antioxidant and neuroprotective effects.
Lee YH, Kim HJ, Yoo H, Jung SY, Kwon BJ, Kim NJ, Jin C, Lee YS.
Bioorg Med Chem (2015) 23 : 4970 -4979
PubMed 26068017 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 18 4.57 4.85

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL163316 3-O-METHYLQUERCETIN 1 4.85
CHEMBL3593745 1 4.78
CHEMBL3593741 1 4.72
CHEMBL3593740 1 4.68
CHEMBL3593755 1 4.66
CHEMBL3593747 1 4.64
CHEMBL3593754 1 4.63
CHEMBL3593744 1 4.58
CHEMBL3593746 1 4.58
CHEMBL3593753 1 4.57
CHEMBL3593743 1 4.56
CHEMBL3593752 1 4.49
CHEMBL196 ASCORBIC ACID 4.0 1 4.39
CHEMBL3593742 1 4.33
CHEMBL3593749 1 4.08
CHEMBL3593751 1 -
CHEMBL3593750 1 -
CHEMBL3593748 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL163316 3-O-METHYLQUERCETIN IC50 = 14170.0 nM 4.85
CHEMBL3593745 IC50 = 16790.0 nM 4.78
CHEMBL3593741 IC50 = 18870.0 nM 4.72
CHEMBL3593740 IC50 = 20740.0 nM 4.68
CHEMBL3593755 IC50 = 22060.0 nM 4.66
CHEMBL3593747 IC50 = 22930.0 nM 4.64
CHEMBL3593754 IC50 = 23180.0 nM 4.63
CHEMBL3593744 IC50 = 26320.0 nM 4.58
CHEMBL3593746 IC50 = 25980.0 nM 4.58
CHEMBL3593753 IC50 = 27040.0 nM 4.57
CHEMBL3593743 IC50 = 27350.0 nM 4.56
CHEMBL3593752 IC50 = 32420.0 nM 4.49
CHEMBL196 ASCORBIC ACID IC50 = 40990.0 nM 4.39
CHEMBL3593742 IC50 = 47160.0 nM 4.33
CHEMBL3593749 IC50 = 84000.0 nM 4.08
CHEMBL3593751 IC50 > 100000.0 nM -
CHEMBL3593750 IC50 > 100000.0 nM -
CHEMBL3593748 IC50 > 100000.0 nM -