Assay Detail
Binding
CHEMBL3594879
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of AMPA receptor in rat hippocampal neurons assessed as inhibition of AMPA-evoked current by whole-cell voltage-clamp method in presence of receptor desensitization inhibitor cyclothiazide
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Tissue | Hippocampus |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
A New Class of Potent N-Methyl-D-Aspartate Receptor Inhibitors: Sulfated Neuroactive Steroids with Lipophilic D-Ring Modifications.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 5.02 | 5.02 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3594112 | — | — | 1 | 5.02 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3594112 | — | IC50 | = | 9500.0 | nM | 5.02 |