Assay Detail
Binding
CHEMBL3595072
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Inhibition of human trypsin measured for 30 mins
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 5 — Multiple protein complex / RNA |
| Curated By | Autocuration |
Publication
Structure-Based Design of Macrocyclic Coagulation Factor VIIa Inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 6 | 5.94 | 7.24 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3594313 | — | — | 1 | 7.24 |
| CHEMBL3594314 | — | — | 1 | 5.57 |
| CHEMBL3594311 | — | — | 1 | 5.52 |
| CHEMBL3594310 | — | — | 1 | 5.44 |
| CHEMBL3594312 | — | — | 1 | - |
| CHEMBL3594305 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3594313 | — | Ki | = | 58.0 | nM | 7.24 |
| CHEMBL3594314 | — | Ki | = | 2700.0 | nM | 5.57 |
| CHEMBL3594311 | — | Ki | = | 3000.0 | nM | 5.52 |
| CHEMBL3594310 | — | Ki | = | 3600.0 | nM | 5.44 |
| CHEMBL3594312 | — | Ki | > | 6000.0 | nM | - |
| CHEMBL3594305 | — | Ki | > | 6000.0 | nM | - |