Assay Detail
Binding
CHEMBL3598442
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of candida albicans beta-(1,3)-glucan synthase assessed as decrease in transfer of radiolabelled glucose from UDP-[3H]-glucose onto acceptor
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Candida albicans |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Beyond substrate analogues: new inhibitor chemotypes for glycosyltransferases
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 6.92 | 9.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3596266 | — | — | 1 | 9.00 |
| CHEMBL3037784 | — | — | 1 | 7.16 |
| CHEMBL2165734 | ENFUMAFUNGIN | — | 1 | 6.00 |
| CHEMBL3596262 | — | — | 1 | 5.52 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3596266 | — | IC50 | = | 1.0 | nM | 9.00 |
| CHEMBL3037784 | — | IC50 | = | 70.0 | nM | 7.16 |
| CHEMBL2165734 | ENFUMAFUNGIN | IC50 | = | 1000.0 | nM | 6.00 |
| CHEMBL3596262 | — | IC50 | = | 3000.0 | nM | 5.52 |