Assay Detail
Binding
CHEMBL3598448
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of ST3N (unknown origin)
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase (CHEMBL3596076) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Beyond substrate analogues: new inhibitor chemotypes for glycosyltransferases
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 4.96 | 5.57 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL338988 | — | — | 1 | 5.57 |
| CHEMBL1170899 | — | — | 1 | 5.00 |
| CHEMBL1170697 | — | — | 1 | 4.30 |
| CHEMBL3596263 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL338988 | — | IC50 | = | 2700.0 | nM | 5.57 |
| CHEMBL1170899 | — | IC50 | = | 10000.0 | nM | 5.00 |
| CHEMBL1170697 | — | IC50 | = | 50000.0 | nM | 4.30 |
| CHEMBL3596263 | — | IC50 | = | 110500.0 | nM | - |