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Assay Detail

CHEMBL3598449

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of ST6N (unknown origin)
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Beta-galactoside alpha-2,6-sialyltransferase 1 (CHEMBL3596075)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Beyond substrate analogues: new inhibitor chemotypes for glycosyltransferases
Tedaldi L, Wagner GK
Medchemcomm (2014) 5 : 1106 -1125
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 3 5.35 6.21

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1170899 1 6.21
CHEMBL1170697 1 5.10
CHEMBL3596263 1 4.73

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1170899 IC50 = 610.0 nM 6.21
CHEMBL1170697 IC50 = 8000.0 nM 5.10
CHEMBL3596263 IC50 = 18500.0 nM 4.73