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Assay Detail

CHEMBL3598451

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of FucT-4 (unknown origin)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Alpha-(1,3)-fucosyltransferase 4 (CHEMBL4996)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Beyond substrate analogues: new inhibitor chemotypes for glycosyltransferases
Tedaldi L, Wagner GK
Medchemcomm (2014) 5 : 1106 -1125
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 5.30 5.75

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL338988 1 5.75
CHEMBL288114 GALLIC ACID 2.0 1 4.85

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL338988 IC50 = 1800.0 nM 5.75
CHEMBL288114 GALLIC ACID IC50 = 14000.0 nM 4.85