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Assay Detail

CHEMBL3598455

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of rat ST6Gal1
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Rattus norvegicus
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Beta-galactoside alpha-2,6-sialyltransferase 1 (CHEMBL4276)
Type SINGLE PROTEIN
Organism Rattus norvegicus

Publication

Beyond substrate analogues: new inhibitor chemotypes for glycosyltransferases
Tedaldi L, Wagner GK
Medchemcomm (2014) 5 : 1106 -1125
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 5.51 5.72

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL122701 1 5.72
CHEMBL222556 1 5.29

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL122701 IC50 = 1900.0 nM 5.72
CHEMBL222556 IC50 = 5100.0 nM 5.29