Assay Detail
Binding
CHEMBL3598457
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of Escherichia coli MurG
3
Total Activities
2
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Escherichia coli |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase (CHEMBL3596078) ↗| Type | SINGLE PROTEIN |
| Organism | Escherichia coli (strain K12) |
Publication
Beyond substrate analogues: new inhibitor chemotypes for glycosyltransferases
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.43 | 5.85 |
| Ki | 1 | 5.89 | 5.89 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3596267 | — | — | 2 | 5.89 |
| CHEMBL262777 | VANCOMYCIN | 4.0 | 1 | 5.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3596267 | — | Ki | = | 1300.0 | nM | 5.89 |
| CHEMBL3596267 | — | IC50 | = | 1400.0 | nM | 5.85 |
| CHEMBL262777 | VANCOMYCIN | IC50 | = | 10000.0 | nM | 5.00 |