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Assay Detail

CHEMBL3598467

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of TNF-alpha activated nuclear factor-kappa B in HEK293 cells after 6 hrs by luciferase reporter gene assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Cell Type HEK293
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Synthesis, molecular docking and anticancer studies of peptides and iso-peptides.
Jabeen F, Panda SS, Kondratyuk TP, Park EJ, Pezzuto JM, Ihsan-ul-Haq, Hall CD, Katritzky AR.
Bioorg Med Chem Lett (2015) 25 : 2980 -2984
PubMed 26048799 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.30 5.30

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL60718 TPCK 1 5.30

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL60718 TPCK IC50 = 5050.0 nM 5.30