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Assay Detail

CHEMBL3598587

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Non-competitive inhibition of Mycobacterium tuberculosis protein tyrosine phosphatase B expressed in Escherichia coli BL21/DE using pNPP substrate by spectrophotometry based Lineweaver-Burk plot analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Mycobacterium tuberculosis
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Diversity-Oriented Synthesis for Novel, Selective and Drug-like Inhibitors for a Phosphatase from Mycobacterium Tuberculosis.
He R, Bai Y, Yu ZH, Wu L, Gunawan AM, Zhang ZY.
Medchemcomm (2014) 5 : 1496 -1499
PubMed 25505942 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 5.82 5.82

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3596431 1 5.82

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3596431 Ki = 1500.0 nM 5.82