Assay Detail
Binding
CHEMBL3598922
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human HDAC11
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Evaluation of histone deacetylase inhibitors (HDACi) as therapeutic leads for human African trypanosomiasis (HAT).
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 7.89 | 10.15 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2105763 | QUISINOSTAT | 2.0 | 1 | 10.15 |
| CHEMBL1851943 | PRACINOSTAT | 3.0 | 1 | 7.37 |
| CHEMBL356769 | TUBACIN | — | 1 | 6.14 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2105763 | QUISINOSTAT | Ki | = | 0.07 | nM | 10.15 |
| CHEMBL1851943 | PRACINOSTAT | Ki | = | 43.0 | nM | 7.37 |
| CHEMBL356769 | TUBACIN | Ki | = | 718.7 | nM | 6.14 |