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Assay Detail

CHEMBL3599620

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiproliferative activity against human U251 cells assessed as decrease in colony formation
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type U-251
Confidence 1 — Organism
Curated By Autocuration

Target

U-251 (CHEMBL615022)
Type CELL-LINE
Organism Homo sapiens

Publication

Progress Toward the Development of Noscapine and Derivatives as Anticancer Agents.
DeBono A, Capuano B, Scammells PJ.
J Med Chem (2015) 58 : 5699 -5727
PubMed 25811651 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.40 4.40

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL364713 NOSCAPINE 2.0 1 4.40

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL364713 NOSCAPINE IC50 = 40000.0 nM 4.40