Assay Detail
Functional
CHEMBL3599895
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of bio-film formation of Bacillus subtilis MTCC 121 incubated for 24 hrs at 37 degC under static conditions by crystal violet staining method
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Bacillus subtilis |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis of novel amide functionalized 2H-chromene derivatives by Ritter amidation of primary alcohol using HBF4·OEt2 as a mild and versatile reagent and evaluation of their antimicrobial and anti-biofilm activities.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 8 | 5.27 | 6.38 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL532 | ERYTHROMYCIN | 4.0 | 1 | 6.38 |
| CHEMBL3596796 | — | — | 1 | 5.85 |
| CHEMBL3596795 | — | — | 1 | 5.29 |
| CHEMBL3596804 | — | — | 1 | 5.06 |
| CHEMBL3596802 | — | — | 1 | 4.65 |
| CHEMBL3596801 | — | — | 1 | 4.36 |
| CHEMBL3596800 | — | — | 1 | - |
| CHEMBL3596803 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL532 | ERYTHROMYCIN | IC50 | = | 420.0 | nM | 6.38 |
| CHEMBL3596796 | — | IC50 | = | 1400.0 | nM | 5.85 |
| CHEMBL3596795 | — | IC50 | = | 5100.0 | nM | 5.29 |
| CHEMBL3596804 | — | IC50 | = | 8800.0 | nM | 5.06 |
| CHEMBL3596802 | — | IC50 | = | 22200.0 | nM | 4.65 |
| CHEMBL3596801 | — | IC50 | = | 43800.0 | nM | 4.36 |
| CHEMBL3596800 | — | IC50 | - | — | - | |
| CHEMBL3596803 | — | IC50 | - | — | - |