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Assay Detail

CHEMBL3602173

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Functional
Antimalarial activity against Plasmodium falciparum NF54 infected in human erythrocytes after 48 hrs by [3H]hypoxanthine incorporation assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Plasmodium falciparum
Confidence 1 — Organism
Curated By Autocuration

Target

Plasmodium falciparum (CHEMBL364)
Type ORGANISM
Organism Plasmodium falciparum

Publication

Highly potent artemisinin-derived dimers and trimers: Synthesis and evaluation of their antimalarial, antileukemia and antiviral activities.
Reiter C, Fröhlich T, Gruber L, Hutterer C, Marschall M, Voigtländer C, Friedrich O, Kappes B, Efferth T, Tsogoeva SB.
Bioorg Med Chem (2015) 23 : 5452 -5458
PubMed 26260339 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 9.06 9.06

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL2393394 1 9.06

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL2393394 IC50 = 0.87 nM 9.06