Assay Detail
Binding
CHEMBL3602207
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]baclofen from GABA-B receptor in cat cerebellum
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Felis catus |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Activation of the γ-Aminobutyric Acid Type B (GABA(B)) Receptor by Agonists and Positive Allosteric Modulators.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.40 | 8.62 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL286077 | — | — | 1 | 8.62 |
| CHEMBL301742 | ARBACLOFEN | 3.0 | 1 | 7.82 |
| CHEMBL302213 | — | — | 1 | 5.75 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL286077 | — | IC50 | = | 2.4 | nM | 8.62 |
| CHEMBL301742 | ARBACLOFEN | IC50 | = | 15.0 | nM | 7.82 |
| CHEMBL302213 | — | IC50 | = | 1770.0 | nM | 5.75 |